- Dec 6 Henry Eustace McCulloch, Brigadier General (Confederate Army), born in Rutherford County, Tennessee (d. 1895)
- Dec 8 August Belmont, Prussian-American financier and diplomat (U.S. Minister to the Netherlands 1853-57), born in Alzey, Hesse, Germany (d. 1890)
- Dec 13 Clement Claiborne Clay, American politician (U.S. Senator from Alabama), born in Huntsville, Alabama (d. 1882)
Werner von Siemens (1816-1892)
Dec 13 German inventor (siemens electrical conductance unit) and industrialist (Siemens corporation), born in Lenthe, German Confederation