- Sep 2 Liliuokalani [Lydia Kamakaʻeha], last queen of Hawaii (1891-93), born in Honolulu, Oʻahu, Kingdom of Hawaii (d. 1917)
- Sep 6 Samuel Arnold, Lincoln conspirator, born in Georgetown, Washington, D.C. (d. 1906)
- Sep 11 John Ireland, Irish-American archbishop of St Paul (1888-1918), born in Burnchurch, Ireland (d. 1918)
- Sep 14 John Pelham, U.S. Confederate artillery major, born in Alexandria, Alabama (d. 1863)
- Sep 16 James J. Hill, Canadian-American railroad entrepreneur (Great Northern Railroad), born in Eramosa Township, Ontario (d. 1916)
- Sep 18 (Anthonij) "Anton" Mauve, Dutch realist painter, and cousin-in-law of Vincent Van Gogh, born in Zaandam, Netherlands (d. 1888)
Victoria Woodhull (1838-1927)
Sep 23 American civil rights activist (1872 presidential candidate, woman's suffrage movement), born in Homer, Ohio