- Sep 2 Roger Wolcott, 39th Governor of Massachusetts (d. 1900)
Jesse James (1847-1882)
Sep 5 American outlaw and son of a clergyman, born in Kearney, Missouri
- Sep 13 Charles Dupee Blake, American composer, born in Walpole, Massachusetts (d. 1903)
- Sep 14 William Edward Ayrton, English Physicist and Inventor, born in London, England (d. 1908)
- Sep 16 Albert Ross Parsons, American composer, born in Sandusky, Ohio (d. 1933)
- Sep 20 Sergey Nechayev, Russian Nihilist (Catechism Revolutionary), born in Ivanovo, Russia (d. 1882)
- Sep 30 Wilhelmina Drucker [Lensing], Dutch feminist and writer (Women's Mutual Protection Society), born in Amsterdam, Netherlands (d. 1925)