- Sep 5 Moritz Gottlieb Saphir, Austrian satirical writer and journalist, dies at 63
- Sep 8 Jacopo Foroni, Italian opera composer (I gladiatori; Advokathen Panthelin), and conductor, dies during cholera epidemic at 34
- Sep 10 Henry Wellington Greatorex, English American composer (Gloria Patri), dies at 44
- Sep 11 Alexander Gurilyov, Russian composer, dies at 55
Dred Scott (c. 1799-1858)
Sep 17 US ex-slave who sought to sue for his freedom, dies of tuberculosis at 62 or 63