- May 3 Joe Ames, American singer and actor (The Ames Brothers Show), born in Malden, Massachusetts (d. 2007)
- May 4 Virginia "Patsy" Garrett, American singer (Fred Waring's Pleasure Time), and actress (Nanny & the Professor), born in Atlantic City, New Jersey (d. 2015)
- May 6 Alan Dewitt, American actor (It's About Time), born in Canton, Ohio (d. 1976)
- May 6 Elizabeth Sellars, Scottish actress ("Chalk Garden"; "A Voyage Round My Father"), born in Glasgow, Scotland (d. 2019) [1]
- May 7 Gale Robbins [Betty Gale Murphy], American singer and actress (Fuller Brush Girl; Mr Hex), born in Chicago, Illinois (d. 1980)
- May 14 Arve Opsahl, Norwegian actor and stand-up comedian (Mot i brøstet, Olsen-banden), born in Oslo, Norway (d. 2007)
- May 16 Harry Carey Jr, American actor (Back to the Future Part III, Gremlins), born in Saugus, California (d. 2012)
- May 19 Daniel Gélin, French actor (Obsession, The Man Who Knew Too Much), born in Angers, Maine-et-Loire (d. 2002)
- May 23 Humphrey Lyttelton, British jazz trumpeter and bandleader ("Bad Penny Blues"), and broadcaster (BBC2 - Best Of Jazz, 1967-2007; BBC4 - I'm Sorry I Haven't A Clue, 1972-2008), born in Eton, Buckinghamshire (d. 2008)
- May 23 James Blish [pseudonym William Atheling, Jr], American-British, sci-fi author (Hugo, Star Trek Reader), born in East Orange, New Jersey (d. 1975)
- May 23 Loren Tindall, American actor (Meet Me on Broadway, Girl of Limberlost), born in Hastings, Oklahoma (d. 1973)
- May 23 Montague Modlyn, English radio and TV broadcaster, born in London, England (d. 1994)
- May 31 Alida Valli [Baroness Alida von Marckenstein-Frauenberg], Italian actress (The Paradine Case, The Third Man), born in Rome, Italy (d. 2006)
- May 31 Howard Reig, American radio and television announcer, born in New York City (d. 2008)
About May 1921
How Old? 103 years old
Generation: Greatest Generation
Leap Year: No
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