- Sep 1 Garry Maddox, American MLB centerfielder, 1972-86 (San Francisco Giants; Philadelphia Phillies - 8X Gold Glove, World Series champ), broadcaster, entrepreneur, and Vietnam War veteran, born in Cincinnati, Ohio
- Sep 10 Bill O'Reilly, American TV host and commentator (The O'Reilly Factor), born in New York City
- Sep 10 Don Muraco, American professional wrestler (WWF), born in Sunset Beach, Hawaii
- Sep 10 Freddy Marks, English actor, singer and entertainer (Rod, Jane and Freddy), born in Smethwick, Worcestershire, England (d. 2021)
- Sep 16 Ed Begley Jr, American actor (Eating Raoul, St Elsewhere, Parenthood), born in Los Angeles, California
- Sep 16 Susan Ruttan, American actress (Roxanne Melman-LA Law), born in Oregon City, Oregon
- Sep 17 Road Runner, Warner Bros. cartoon character created by Chuck Jones (Looney Tunes and Merrie Melodies series), first debuts in "Fast and Furry-ous"
- Sep 17 Wile E. Coyote, Warner Bros. cartoon character created by Chuck Jones (Looney Tunes and Merrie Melodies series), first debuts in "Fast and Furry-ous"
Twiggy (74 years old)
Sep 19 English model and actress (Boyfriend, W), born in Neasden, Middlesex, England
- Sep 20 Anthony Denison, American actor (The Closer), born in New York
- Sep 23 Floella Benjamin, Trinidadian-British actress, presenter (Play School) and politician, born in Pointe-à-Pierre, Trinidad and Tobago
- Sep 25 Anson Williams, American actor (Potsie-Happy Days), born in Los Angeles, California
- Sep 25 Mimi Kennedy, American actress (Spencer, 3 girls 3, Under 1 Roof), born in Rochester, New York
- Sep 25 Pedro Almodovar, Spanish filmmaker (Women the Verge of a Nervous Breakdown, Matador), born in Calzada de Calatrava, Spain
- Sep 27 Robb Weller, American TV host (Entertainment Tonight, Home Show)
- Sep 29 Tony Hoty, American actor (Ransom, Paper), born in Cleveland, Ohio
About September 1949
How Old? 74 years old
Generation: Baby Boomer
Leap Year: No
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