- May 1 Douglass Watson, American actor (Satan Murders, Another World), dies at 68
- May 1 Marion Mack, actress (General), dies
- May 3 Muriel Ostriche, American silent film actress dies at 92
- May 15 Johnny Green, American singer (Body and Soul) and film score composer who won 5 Academy Awards, dies at 80
- May 19 Anton Diffring [Alfred Pollack], German character actor (Assignment Vienna), dies of cancer at 72
- May 19 Robert Webber, American actor (12 Angry Men, Moonlighting, 79 Park Avenue), dies of Lou Gehrig's disease at 64
- May 20 Gilda Radner, American comedian and actress (SNL, 1975-80; Haunted Honeymoon), dies of ovarian cancer at 42
- May 27 Jack Starrett, director/actor (Chase, Nightwish, 1st Blood), dies
- May 31 Terry Drinkwater, American CBS news correspondent, dies at 53 of cancer
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