- May 2 Gina Mastrogiacomo, American actress (Goodfellas), dies at 39
- May 2 Ted Rogers, British comedian and game show host (3-2-1), dies after emergency open-heart surgery at 65
- May 4 Bonnie Lee Bakley, American second wife of actor Robert Blake murdered in her car outside a Studio City, California restaurant at 44
- May 10 Deborah Walley, American actress (b. 1943)
- May 12 (Pierino) Perry Como, American singer ("Catch A Falling Star") and TV personality (The Perry Como Show), dies at 89
- May 13 Jason Miller, American actor and writer (Exorcist, Light of Day), dies at 62
- May 22 Jack Watling, British actor (Nanny, Adventure for 2, Naked Heart), dies at 78
- May 22 Whitman Mayo, American actor (Grady Wilson-"Sanford & Son"), dies at 70
- May 26 Anne Haney, American actress (Mrs. Doubtfire - "Mrs. Sellner"; Liar Liar - "Greta"), dies of congestive heart failure at 67
- May 27 Ramon Bieri, American actor (Badlands, The Andromeda Strain), dies at 71
- May 31 Arlene Francis, American actress and radio and television personality (What's My Line?), dies at 93
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