- Oct 7 Patrice Chéreau, French opera director and actor (Danton), dies from lung cancer at 68
- Oct 10 Kumar Pallana, Indian character actor and vaudevillian (Bottle Rocket, Rushmore), dies at 94
- Oct 11 Stu Gilliam, American actor and comedian (Roll Out, Harris & Company), dies at 80
- Oct 12 Eduard Martsevich, Soviet-Russian actor and People's Artist of the RSFSR, dies at 76
- Oct 13 Tommy Whittle, British jazz tenor saxophonist (Ted Heath; BBC Show Band), and bandleader, dies of pneumonia on his 87th birthday
- Oct 16 Ed Lauter, American actor (The Artist, The Number 23), dies from mesothelioma at 74
- Oct 18 Mary Carver [Carvellas], American actress (Simon & Simon, Star Trek: Enterprise), dies at 89
- Oct 19 Noel Harrison, British singer and actor, dies of a heart attack at 79
- Oct 25 Marcia Wallace, American actress (The Bob Newhart Show - "Carol"), dies from pneumonia at 70
- Oct 25 Nigel Davenport, British actor (Without a Clue, Masada), dies at 85