- Sep 1 Novella Nelson, American actress (Antwone Fisher, Purlie, Chiefs), dies at 78
- Sep 1 Shelley Berman, American Grammy Award-winning comedian, actor (Son of Blob; Divorce American Style; Curb Your Enthusiasm), writer, and educator, dies of complications from Alzheimer's disease at 92
- Sep 2 Murray Lerner, American documentary and experimental film director and producer (Secrets of the Reef), dies at 90
Harry Dean Stanton (1926-2017)
Sep 15 American actor (Lucky; Alien; Cool Hand Luke; The Godfather Part II), musician, and singer, dies at 91
- Sep 17 Bobby "The Brain" Heenan, American pro wrestling manager, colour commentator and wrestler (WWE Hall of Fame), dies of throat cancer at 72
- Sep 19 Bernie Casey, American actor (Boxcar Bertha, Rent-a-Cop), dies at 78
- Sep 25 Anthony "Tony" Booth, British actor and father of Cherie Blair (Till Death Us Do Part), dies at 85
- Sep 27 Anne Jeffreys [Annie Carmichael], American singer and actress (Dick Tracy; Topper; General Hospital), dies at 94
- Sep 28 Chuck Low, American actor (Goodfellas; Once Upon a Time in America), dies at 89
- Sep 30 Elizabeth Baur, American actress (Fran-Ironside, Teresa-Lancer), dies at 69
- Sep 30 Monty Hall, Canadian-American TV game show host (Let's Make a Deal), dies at 96