- May 1 Andrés Reyes [Universo 2000], Mexican pro wrestler (3 x CMLL World Heavyweight Championship), dies from a heart attack at 55
- May 1 Javier Aller, Spanish actor (The Biggest Robbery Never Told), dies at 46 of complications from diabetes
- May 1 Sun Yueh, Chinese-born Taiwanese actor (Papa, Can You Hear Me Sing), dies of sepsis at 87
- May 2 Wang Danfeng, Chinese actress, dies at 93
- May 2 Wolfgang Völz, German actor, dies at 87
- May 4 Cathy Godbold, Australian actress (The Saddle Club, Home and Away), dies of brain cancer at 43
- May 5 Ermanno Olmi, Italian film director (The Tree of Wooden Clogs), dies at 86
- May 8 Anne V. Coates, British film editor (1962 Oscar, Lawrence of Arabia), dies at 92
- May 11 Josh Greenfeld, American author and screenwriter (A Child Called Noah), dies at 90
- May 13 Margot Kidder, Canadian American actress (Lois Lane in Superman films, Amityville Horror), dies at 69
- May 16 Joseph Campanella, American character actor (Guiding Light, Mannix), dies at 93
- May 18 Stephanie Adams, American Playboy playmate (November 1992), kills herself and her child at 47
- May 20 Patricia Morison, American actress (Peyton Place, Dressed to Kill, Kiss Me, Kate The King and I), dies at 103
- May 21 Clint Walker, American actor (Kodiak, Cheyenne, Dirty Dozen), dies at 90
- May 23 Glynn Edwards, English television actor, dies at 87
- May 24 Jerry Maren [Gerard Marenghi], American actor (The Wizard of Oz; Mayor McCheese), dies at 98
- May 26 Ted [Samuel Frederick] Dabney, American electrical engineer and founder of Atari (Pong), dies at 81
- May 27 Russell Nype, American singer and actor (The Stuff,;Call Me Madam; Dorothy), dies at 98
- May 28 Cornelia Frances [Zulver], British-Australian actress (Home and Away), dies from bladder cancer at 77
- May 28 María Dolores Pradera, Spanish melodic singer and actress, dies at 93
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