Otto von Bismarck (1815-1898)
Apr 1 German chancellor (1866-90) who helped unify Germany, born in Schönhausen, Prussia
- Apr 6 Robert Volkmann, German composer and pedagogue, born in Lommatzsch, Kingdom of Saxony (d. 1883)
- Apr 11 Clara Fey, German Roman Catholic Nun and the founder of the Sisters of the Poor Child Jesus, born in Aachen, Prussia (d. 1894)
- Apr 12 Henry Hugo Pierson, English composer, born in Oxford, England (d. 1873)
- Apr 24 Anthony Trollope, English novelist and poet (Barchester Towers), born in London (d. 1882)
- Apr 24 James E. Harrison, Brigadier General (Confederate Army), born in Greenville District, South Carolina (d. 1875)
- Apr 28 Andrew Jackson Smith, American Major General (Union Army), born in Livingston County, Kentucky (d. 1897)
- Apr 29 Abram Duryée, American Brevet Major General (Union Army), born in New York City (d. 1890)
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