- Apr 6 Adamántios Koraïs, Greek humanist scholar, dies at 84
- Apr 7 Antoni Radziwiłł, Polish-Lithuanian politician, cellist, and composer, dies at 57
- Apr 11 Rowland Hill, English preacher who advocated for the smallpox vaccine, dies at 88
- Apr 22 Richard Trevithick, English inventor (steam locomotive), dies at 62
Assassination
Drug Overdose
Gunshot Wound
Murder
Plane Crash
Suicide