- Jan 12 Adrian van Utrecht, Flemish still life painter, born in Antwerp (d. 1652)
Alexander VII (1599-1667)
Feb 13 Italian Pope (1655-67), born in Siena, Florence, Italy
- Mar 8 Suzanna van Baerle, Dutch poet ("Dagh-werck" written with her husband, Constantijn Huygens), born in Amsterdam (d. 1637)
- Mar 13 Johannes Berchmans, Dutch Jesuit and Roman Catholic saint, born in Diest, Seventeen Provinces (d. 1621)
- Mar 22 Anthony Van Dyck, Flemish painter (Charles I of England), born in Antwerp, Spanish Netherlands (d. 1641)
- Mar 23 Thomas Selle, German baroque composer, born in Zörbig, Electorate of Saxony, Holy Roman Empire (d. 1663)
- Mar 28 Witte Corneliszoon de With, Dutch naval officer, born in Brielle, Netherlands (d. 1658)
Oliver Cromwell (1599-1658)
Apr 25 English general and puritan Lord Protector of England (1653-58), born in Huntingdon, Huntingdonshire, England
- Jun 6 Diego Velázquez, Spanish painter (Las Meninas), baptized in Sevilla, Spain (d. 1660)
- Jun 12 Johan Wolfert van Brederode, Dutch governor (Hertogenbosch) and field marshal, born in Heusden, Noord-Brabant, Netherlands (d. 1655)
- Aug 14 Méric Casaubon, French-English classical scholar, born in Geneva (d. 1671)
- Sep 20 Christian the Younger, German Protestant military leader during the Thirty Years' War, born in Gröningen, Germany (d. 1626)
- Sep 25 Francesco Borromini, Italian sculptor and architect, born in Bissone, Italy (d. 1667)
- Oct 10 Jacob Aertsz Colom, Dutch publisher (Consolation of the Sea), born in Dordrecht, Netherlands (d. 1673)
- Oct 29 Marie de l’Incarnation [Marie Guyart], French Ursline nun, teacher and saint (established Catholicism in New France), baptized in Tours, France (d. 1674) [1]
- Oct 31 Denzil Holles, 1st Baron Holles, English statesman and writer, born in Houghton, England (d. 1680)
- Nov 11 Prince Ottavio Piccolomini, Italian nobleman, Duke of Amalfi, and field marshal of the Holy Roman Empire, born in Florence, Grand Duchy of Tuscany (now Italy) (d. 1656)
Year of the Rabbit
Year of the Dragon
Year of the Snake
Year of the Horse
Year of the Goat/Sheep
Year of the Monkey