- Feb 25 Simon Stijl, Frisian physician and writer, born in Harlingen (d. 1804)
- Mar 7 Jean-Louis Laruette, French musician and composer of comic opera, born in Paris, France (d. 1792)
- Mar 11 Robert Treat Paine, American judge and Founding Father (signed US Declaration of Independence), born in Boston, Massachusetts (d. 1814)
- Apr 4 Francesc Morera i Cots, Valencian composer, born in Sant Mateu, Spain (d. 1793)
- Apr 23 William Williams, American merchant (signed US Declaration of Independence), born in Lebanon, Connecticut (d. 1811)
- May 11 Johann Gottfried Seyfert, German composer and violinist, born in Augsburg, Electorate of Bavaria, Holy Roman Empire (d. 1772)
- May 26 Orazio Mei, Italian organist, and composer, born in Pisa, The Papal States (now Italy) (d. 1788)
Martha Washington (1731-1802)
Jun 13 1st US First Lady (1789-97), born in Kent County, Virginia
- Jul 3 Samuel Huntington, American politician and signer of the Declaration of Independence, born in Windham, Connecticut (d. 1796)
- Aug 4 Giuseppe Colla, Italian composer, born in Parma, Duchy of Parma and Piacenza (now Italy) (d. 1806)
- Sep 2 Johann Friedrich von Cronegk, German poet and playwright (Olint und Sophronia), born in Ansbach (d. 1758)
- Sep 7 Damasus Brosmann, Moravian composer, born in Fulnek, Czech Republic (d. 1798)
- Sep 7 Elisabetta de Gambarini, English composer, born in Holles Street, St Marylebone, Middlesex (d. 1765)
- Sep 9 Francisco Javier Clavijero, Mexican Jesuit teacher and writer, born in Veracruz, Mexico (d. 1787)
- Oct 10 Henry Cavendish, England, physicist and chemist (discovered hydrogen), born in Nice (d. 1810)
- Nov 1 Theodore-Jean Tarade, French composer, born in Paris, France (d. 1788)
Benjamin Banneker (1731-1806)
Nov 9 African American astronomer, mathematician and surveyor of Washington, D.C., born in Ellicott's Mills, Maryland
- Nov 11 Carl Joseph Toeschi, German composer, born in Ludwigsburg, Baden-Württemberg, Germany (d. 1788)
- Nov 26 William Cowper, English pre-romantic poet (His Task), born in Berkhamsted, Hertfordshire, England (d. 1800)
- Nov 27 Gaetano Pugnani, Italian violinist and composer, born in Turin, Italy (d. 1798)
- Dec 6 Sophie von Laroche, German writer (History of Lady Sophia Sternheim), born in Kaufbeuren. Bavaria (d. 1807)
- Dec 7 Abraham-Hyacinthe Anquetil-Duperron, French scholar and interpreter, born in Paris (d. 1805)
- Dec 8 František Xaver Dušek, Czech composer, born in Chotěborky, Jaroměř, Czech Republic (d. 1799)
- Dec 12 Erasmus Darwin, influential English physician, poet, philosopher, and botanist (grandfather of Charles Darwin), born in Newark-on-Trent, England (d. 1807)
- Dec 26 Anthony Ziesenis, Dutch architect and sculptor (Town Hall of Westzaan) (d. 1801)
- Dec 28 Christian Cannabich, German violinist, composer and royal chaplain master, born in Mannheim, Electorate of the Palatinate, Holy Roman Empire (d. 1798)