- Jan 8 Thomas Ebendorfer, Austrian historian (b. 1385)
- Feb 23 Zhu Qizhen, Chinese Emperor Yingzong of Ming (1435-49 and 1457-64), dies at 36 but not before giving an order to end the practice of burying alive concubines and palace maids so that they could follow emperors to the next world
- May 17 Thomas de Ros, 9th Baron de Ros of Helmsley, English politician, executed at 36
- Jun 18 Rogier van der Weyden, Flemish painter, dies at 65
Cosimo de' Medici (1389-1464)
Aug 1 Italian banker, de facto ruler of Florence and patron of the arts, dies at 74
Assassination
Drug Overdose
Gunshot Wound
Murder
Plane Crash
Suicide