- Jan 5 Ercole Procaccini, Italian painter, dies
- Jan 16 Murad III, Ottoman Sultan (1574-95), dies at 48
- Jan 24 Ferdinand II, Archduke of Austria, Governor of Bohemia, dies at 65
- Feb 12 Archduke Ernest of Austria, Governor of the Spanish Netherlands, son of Holy Roam Emperor Maximilian II,dies at 41
- Feb 20 Ernst, Archduke of Austria (son of Maximilian II Holy Roman Emperor), dies at 41
- Feb 21 Robert Southwell, English Roman Catholic priest and Jesuit and poet, hung drawing, and quartered for treason at 33 (canonized 1970)
- Apr 25 Torquato Tasso, Italian poet (Gerusalemme liberata), dies at 51
- May 25 Valens Acidalius, German critic and poet (b. 1567)
- May 26 Philippus Nerius [Filippo Neri], Italian merchant/saint, dies at 79
- Aug 24 Thomas Digges, English astronomer (Universe Infinite), dies
- Aug 26 Antonio, Prior of Crato, claimant to the throne of Portugal (b. 1531)
- Oct 15 Abu al-Faiz ibn Mubarak Faizi, Persian-Dutch East iIndies poet, dies at 48
- Nov 8 Peter Opmeer, Dutch church historian and humanist (Historia Martyrum), dies at 69
- Nov 12 John Hawkins, English naval commander, Treasurer of the Navy, and early English slave trader, dies at sea at 63
- Nov 29 Alonso de Ercilla y Zúñiga, Basque soldier and poet, dies at 61
- Dec 10 Reynier Cant, mayor of Amsterdam, dies at about 59
Assassination
Car Crash
Hanging
Killed in Action
Plane Crash
Poisoning