- Jan 1 Cornelis Pieterse Hoft, Amsterdam merchant & regent, dies at 68
- Jan 21 John Dowland, English composer (In Darkness We Dwell), dies at 62
- Jan 24 Samuel Argall, English adventurer and naval officer, dies at 45
- Feb 7 William V, Duke of Bavaria (b. 1548)
- Feb 11 Pietro Cataldi, Italian mathematician, dies at 77
- Feb 20 John Dowland, British (or Irish?) Renaissance lutenist, singer, and composer ("I saw my Lady weepe"; "Flow My Tears"), dies and is buried at 63
- Feb 28 Cyril Tourneur, English poet/dramatist, dies at about 51
Francis Bacon (1561-1626)
Apr 9 English statesman, Lord Chancellor (1617-21) and philosopher (Novum Organum), dies from pneumonia at 65
- Apr 11 Marin Getaldić, Croatian mathematician (b. 1568)
- May 4 Arthur Lake, English Bishop of Bath and Wells, and translator of the King James Bible, dies at 56
- May 17 Juan Pujol, Catalan composer, dies at 56
- Jun 7 Anne of Saint Bartholomew, Flemish Roman Catholic nun, dies at 76
- Jun 16 Christian the Younger, Duke of Brunswick-Lüneburg-Wolfenbüttel, German Protestant military leader during the Thirty Years' War, dies at 26
- Jul 5 Stephan Fadinger, Austrian boer leader, dies in battle
- Jul 13 Robert Sidney, 1st Earl of Leicester, English statesman, dies at 62
- Sep 21 François de Bonne, duc de Lesdiguières, Constable of France (b. 1543)
- Sep 26 Lancelot Andrewes, English theologist/bishop of Winchester, dies at 71
- Sep 26 Wakisaka Yasuharu, Japanese warrior (b. 1554)
- Sep 30 Nurhaci, Manchurian chief, founding Khan of Later Jin (b. 1559)
- Oct 2 Diego Sarmiento de Acuña, 1st Count of Gondomar, Spanish diplomat, dies at 58
- Oct 30 Willebrord Snellius (also Snell and Snel van Royen), Dutch astronomer/mathematician, dies at about 46
- Nov 25 Edward Alleyn, English actor and founder of Dulwich College, dies at 60
- Nov 29 Ernst, Graf von Mansfield, German soldier (c. 1580)
- Nov 30 Thomas Weelkes, English organist and composer of madrigals, dies at 47
- Dec 8 John Davies, English poet (b. 1569)
- Dec 10 Edmund Gunter, English mathematician (b. 1581)
- Dec 15 Adriaen de Vries, Dutch sculptor/painter, dies at about 70
Assassination
Drug Overdose
Gunshot Wound
Murder
Plane Crash
Suicide