- Jan 28 Richard Allestree, English royalist churchman (b. 1619)
- Feb 14 Francesco Nigetti, Italian composer, dies at 77
- Mar 12 Frans van Mieris the Elder, Dutch painter, dies at 45
- Apr 9 Alfonso Marsh, English composer and lutenist, dies at 54
- May 24 Nicodemus Tessin the Elder, Swedish architect (Drottningholm Palace), dies at 65
- May 25 Pedro Calderón de la Barca, Spanish dramatist, poet and writer of the Spanish Golden Age, dies at 81
- Jun 9 William Lilly, English astrologer (Christian Astrology), dies at 79
- Jul 1 Oliver Plunkett, Catholic Archbishop of Armagh and last Catholic martyr (later beatified) to die in England, hanged, drawn and quartered for treason at Tyburn at 55
- Jul 5 Fjodor Aleksejevitsj, tsar of Russia, dies
- Jul 8 Georg Neumark, German composer and poet, dies at 60
- Jul 25 Urian Oakes, English-born President of Harvard University (b. 1631)
- Aug 17 Nikon [Nikita Minin], patriarch of Russian-orthodox church, dies at 76
- Oct 7 Nicolaas Heinsius, Dutch philological, classical scholar and diplomat, dies at 61
- Dec 8 Gerard Terborch, the Younger, Dutch painter/etcher, dies
- Dec 22 Richard Alleine, English Puritan clergyman (b. 1611)
Assassination
Car Crash
Hanging
Killed in Action
Plane Crash
Poisoning