- Jan 15 Charles-Hubert Gervais, French baroque composer, dies at 72
- Jan 23 Giambattista Vico, Italian philosopher and historian (New Science), dies at 75
- Jan 25 Domenico Natale Sarro, Italian opera composer, dies at 64
- Jan 26 Ludwig Andreas Graf Khevenhüller, Austrian field marshal, dies at 60
- Feb 14 John Hadley, English mathematician and inventor (octant), dies at 61
- Feb 15 František Václav Míča, Czech conductor and composer, dies at 49
- Feb 29 John Theophilus Desaguliers, French-British natural philosopher and freemason, dies at 60
- Mar 3 Jean Barbeyrac, French jurist
- Mar 4 John Anstis, English Garter King of Arms, dies at 74
Anders Celsius (1701-1744)
Apr 25 Swedish astronomer (proposed the Celsius temperature scale), dies at 42
Alexander Pope (1688-1744)
May 30 English poet (The Rape of the Lock, translation of Homer), dies at 56
- Jun 14 Andre Campra, French composer, dies at 83
- Jul 14 Immanuel J. Pyra, German poet (Temple of True Poetry), dies at 28
- Aug 9 James Brydges, 1st Duke of Chandos, English patron of the arts (George Frideric Handel) (b. 1673)
- Aug 13 John Cruger, Dutch-born Mayor of New York (b. 1678)
- Aug 19 Carlo Arrigoni, Italian composer and musician, dies at 46
- Oct 18 Sarah Churchill, Duchess of Marlborough, close friend of Queen Anne of Great Britain, dies at 84
- Oct 31 Leonardo Ortensio Salvatore de Leo, Italian opera composer, dies at 50
- Dec 8 Marie-Anne de Mailly-Nesle, duchess de Châteauroux, French mistress of King Louis XV of France, dies at 28
- Dec 23 Élisabeth Charlotte d'Orléans, Duchess of Lorraine, dies at 68