- Jan 1 Martin Heinrich Klaproth, German chemist (discovered uranium), dies at 73
- Jan 12 Juan Andres, Spanish Jesuit (b. 1740)
- Jan 14 Pierre-Alexandre Monsigny, French composer, dies at 87
- Jan 16 Alexander J. Dallas, American statesman and financier, dies at 57
- Jan 16 Antonín Volánek, Czech organist and composer, dies at 55
- Jan 28 Friedrich Ludwig Æmilius Kunzen, German composer, dies at 55
- Feb 8 Francis Horner, Scottish political economist and politician (1810 Bullion Report), dies of ill health at 38
- Feb 9 Franz Wilhelm Tausch, German clarinetist, composer, and pedagogue, dies at 54
- Feb 18 Giacomo Quarenghi, Italian-Russian master builder and architect (Hermitage Theater), dies at 72
- Feb 20 Martin de Ron, Swedish bassoonist and composer, dies at 27
- Mar 1 Luigi Gatti, Ittalian tenor, kapellmeister, priest, and composer, dies at 77
- Mar 8 Wentworth Cheswell, American auditor, teacher, Revolutionary War messenger, 1st African American elected to public office, dies of typhus fever at 70
- Mar 13 Matej Sojka, Bohemian composer, dies at 77
- Mar 18 Johann Jakob Walder, Swiss composer and politician, dies at 67
- Apr 2 Johann Heinrich Jung, German author (Heinrich Stillings Leben), dies at 76
- Apr 4 André Masséna, Duke of Rivoli, Prince d'Essing and Marshal of France (b. 1758)
- Apr 6 Bonaventura Furlanetto, Italian composer, dies at 78
Charles Messier (1730-1817)
Apr 12 French astronomer, comet hunter and cataloguer of nebulae and star clusters, now referred to as "M objects", dies at 86
- May 21 Johann Friedrich Christmann, German composer, dies at 64
- Jun 13 Richard Edgeworth, Anglo-Irish inventor and educationalist, dies at 73
- Jun 18 Joannes Siberg, Dutch Governor-General of the Dutch East Indies (1801-05), dies
- Jun 23 Otto Carl Erdmann Kospoth, Prussian composer, dies at 63
- Jun 24 Thomas McKean, American attorney and politician (signed US Declaration of Independence), dies at 83
- Jun 30 Abraham Gottlob Werner, German geologist
- Jul 14 Madame de Staël [Anne Louise Germaine de Staël-Holstein], French-Swiss author (De l’Allemagne), dies at 51
- Aug 7 Pierre Samuel du Pont de Nemours, French industrialist (b. 1739)
- Aug 10 Francis Cabot Lowell, American mill owner (founded 1st raw cotton-to-cloth textile mill), dies at 42
- Sep 9 Paul Cuffe, African American civil rights activist (helped settle Sierra Leone), dies at 58
- Oct 2 Fyodor Fyodorovich Ushakov, Russian naval commander and admiral (b. 1744)
- Oct 12 Johann Franz Xaver Sterkel, German organist, pianist, kapellmeister, composer, and priest, dies at 66
- Oct 15 Johann Ludwig Burckhardt, Swiss traveller and orientalist, 1st European to discover Petra and Abu Simbel, dies at 32
Tadeusz Kościuszko (1746-1817)
Oct 15 Polish-Lithuanian military leader and statesman considered a national hero, dies at 71 after falling from a horse, developing a fever and suffering a stroke
- Oct 16 Manuel C Piar, Curacaos/Venezulian freedom writer, dies
- Oct 18 Etienne-Nicolas Méhul, French opera composer, dies at 54
- Oct 26 Nikolaus Joseph von Jacquin, Austrian scientist (b. 1727)
- Nov 1 Giovanni Zanotti, Italian composer, dies at 79
- Nov 6 Charlotte Augusta of Wales, British princess and only legitimate grandchild of George III, dies in childbirth at 21
- Nov 7 Francesco Pasquale Ricci, Italian composer, dies at 85
- Nov 8 Andrea Appiani, Italian royal painter (Napoleon), dies at 63
- Nov 14 Policarpa Salavarrieta, Colombian revolutionary (b. 1795)
- Dec 1 Justin Heinrich Knecht, German composer, dies at 65
William Bligh (1754-1817)
Dec 7 British naval officer of "HMS Bounty" fame, dies at 63
- Dec 11 Max von Schenkendorf, German poet, dies at 34
- Dec 12 Emperor Tekle Giyorgis I of Ethiopia, (b. about 1751)
- Dec 15 Maria Walewska [Leszczinska], Polish lover of Emperor Napoleon I, dies at 31
- Dec 16 Pattimura [Thomas Matulesia] Ambonese soldier and leader of a rebellion against the Dutch (now Indonesian national hero), hung at Fort Victoria at 33 or 34 [1]