- Jan 17 Daniel Albert Wyttenbach, German-Swiss classicl scholar and historian, dies at 73
- Jan 23 Prince Edward, British Duke of Kent and Strathearn, son of Geor III and father of Queen Victoria, dies of pneumonia at 52
- Jan 25 Joseph Franz Weigl, German cellist and early proponent of the 'thumb technique', dies at 79
George III (1738-1820)
Jan 29 King of Great Britain and Ireland and King/Elector of Hanover (1760-1820), dies after years of mental illness at 81
- Feb 7 Samuel Adams Holyoke, American composer, dies at 57
- Feb 12 Guillaume Albert Teniers, Flemish composer, dies at 71
- Feb 14 Charles Ferdinand, Duke of Berry, son of French King Charles X, assassinated by a Bonapartist at 42
- Feb 14 Cosme Argerich, Argentine physician and founder of the Medicine School of Buenos Aires, dies at 61
- Feb 15 Pierre-Joseph Cambon, French member of Committee of Salut Public, dies at 63
- Feb 15 William Ellery, US attorney (signed US Declaration of Independence), dies at 92
- Feb 16 Georg Carl von Döbeln, Swedish Lieutenant General and war hero, dies at 61
- Feb 29 Johann Joachim Eschenburg, German literary critic (b. 1743)
- Mar 11 Benjamin West, Anglo-American painter (Death of General Wolfe), dies at 81
Alexander Mackenzie (Explorer) (c. 1764-1820)
Mar 12 Scottish born Canadian explorer, First European to cross North America, dies at roughly 56
- Mar 15 Clemens Maria Hofbauer, patron saint of Vienna (b. 1751
- Mar 22 Stephen Decatur, American military hero Commodore (War of 1812), killed in a duel with Commodore James Barron at 41
- Mar 26 Jean-Etienne Despreaux, French ballet dancer and composer, dies at 71
- Apr 5 Henrik Constantijn Cras, Dutch lawyer (Laudatio Hugonis Grotii), dies at 81
- Apr 8 Thomas Douglas, 5th Earl of Selkirk, Scottish philanthropist, dies at 48
- Apr 20 Arthur Young, English writer on agriculture (Annals of Agriculture), dies at 78
- May 10 Matthäus Stegmayer, Austrian composer, dies at 49
- May 12 Jacob Andries van Braam, Dutch merchant and colonial administrator (Suriname), dies at 49
- May 14 Paul Friedrich Struck, composer, dies at 43
- Jun 9 Wilhelmina of Prussia, Princess of Orange (1767-1806), dies at 68
Joseph Banks (1743-1820)
Jun 19 English botanist and naturalist who accompanied James Cook on board the Endeavour, dies at 77
Manuel Belgrano (1770-1820)
Jun 20 Argentine politician and military leader who took part in the Argentine Wars of Independence and created the Flag of Argentina, dies at 50
- Jun 29 Florido Toméoni, Italian composer, and playwright, dies at 55
- Aug 6 Antonin Vranicky, Czech composer and violinist, dies at 59
- Aug 6 Princess Frederica Charlotte of Prussia, Duchess of York and Albany, dies at 53
- Aug 7 Élisa Bonaparte, Corsican sister of Napoleon who appointed her Princess of Lucca and Piombino and Grand Duchess of Tuscany, dies at 43
- Aug 11 János Lavotta, Hungarian violinist and composer, dies at 56
- Aug 28 Andrew Ellicott, American surveyor (b. 1754)
- Sep 2 Jiaqing [Yongyan], 5th Emperor of Qing Dynasty (1796-1820), dies at 59
- Sep 3 Benjamin Henry Latrobe, American architect (completed U.S. Capitol), dies at 56
- Sep 7 Court Lambertus van Beyma, Frisian regent and leader of the Frisian patriots, dies at 67
- Sep 17 Henri Hamal, Belgian composer, dies at 76
- Sep 21 Joseph Rodman Drake, American poet (American Flag), dies of consumption at 25
Daniel Boone (1734-1820)
Sep 26 American frontiersman and explorer (US Hall of Fame 1915), dies at 85
- Oct 3 Ludwig Wenzel Lachnith, Bohemian horn player and composer, dies at 74
- Oct 8 Henri Christophe, President of Haiti (1807-11) and King of Haiti (1811-20), dies at 53
- Oct 12 Elias Annes Borger, Dutch theologist and poet (By the Rhine), dies at 36
- Oct 15 Karl Philipp, Prince of Schwarzenberg, Austrian field marshal, dies at 49
- Dec 21 Charles-Francois Dumonchau, French pianist and composer, dies at 45