- Dec 1 Sam Levene, American Broadway actor (Purple Heart, Designing Women), dies at 75
- Dec 2 Richard Pindle Hammond, American composer dies at 83
- Dec 2 Romain Gary [Roman Kacew], Lithuanian-French writer, also published as Émile Ajar (Les racines du ciel; La vie devant soi), diplomat, and screenwriter (The Longest Day), dies of a self-inflicted gunshot at 66
Oswald Mosley (1896-1980)
Dec 3 British politician and founder of British Union of Fascists, dies at 84
John Lennon (1940-1980)
Dec 8 British musician, pop star and member of The Beatles (Imagine), shot and murdered outside of his home in NYC by Mark David Chapman at 40
Elston Howard (1929-1980)
Dec 14 American baseball catcher (12 × MLB All-Star; 6 × World Series; AL MVP 1963; first African-American NY Yankee), dies from myocarditis at 51
Colonel Sanders (1890-1980)
Dec 16 American founder of Kentucky Fried Chicken, dies at 90
- Dec 16 Hellmuth Walter, German engineer and inventor (b. 1900)
Alexei Kosygin (1904-1980)
Dec 18 Soviet statesman and Premier of the Soviet Union (1964-80), dies of a heart attack at 76
Marc Connelly (1890-1980)
Dec 21 American playwright (One Minute Please), dies at 90
Karl Dönitz (1891-1980)
Dec 24 German naval admiral and last leader of Nazi Germany, dies of a heart attack at 89
- Dec 24 Siggie Nordstrom, American singer (The Nordstrom Sisters), dies at 87
- Dec 25 (Ludwig) "Louis" Neefs, Belgian pop singer (Eurovision, 1967 & 1969), dies, along with his wife, in a car accident at 43
- Dec 25 Fred Emney, British actor (Let the People Sing; Adventures of a Private Eye; Lilac Domino), dies at 80
- Dec 26 (John) "Peck" Kelley, American jazz pianist and bandleader (Peck's Bad Boys), dies from complications of Parkinson's disease at 82
- Dec 26 Tony Smith, American sculptor (b. 1912)
- Dec 28 Amir Elahi, Pakistani cricket spin bowler (1 Test India, 5 Tests Pakistan), at 72
- Dec 28 Jersey calf, lived 222 days with an artificial heart
- Dec 29 Nadezhda Mandelstam, Russian writer (b. 1899)
- Dec 29 Roy Engle, American writer and actor (The Man from Planet X, The Wild Wild West, My Favorite Martian), dies from meningitis at 67
- Dec 29 Tim Hardin, American singer (If I Were a Carpenter, Reason to Believe), dies of a drug overdose at 39
- Dec 31 Arthur Wellard, English cricket all-rounder (2 Tests, 7 wickets, BB 4/81; Somerset CCC), dies at 78
- Dec 31 Bob Shawkey, American baseball pitcher (World Series 1923, 27; AL ERA leader 1920, New York Yankees), dies at 90
Marshall McLuhan (1911-1980)
Dec 31 Canadian writer and 'prophet of the digital age' (the medium is the message), dies at 69
- Dec 31 Raoul Walsh, American director (High Sierra), dies at about 88