- May 1 Henry Cooper, English boxer (British, European, C'wealth heavyweight champion; famous defeats to Muhammad Ali 1963, 66), dies of heart failure at 76
- May 1 Ted Lowe, English snooker commentator (Pot Black, BBC), dies at 90
Osama bin Laden (1957-2011)
May 2 Islamic militant and founder of al-Qaeda, shot and killed in Abbottabad, Pakistan by navy seals during Operation Neptune Spear at 54
- May 3 Jackie Cooper, American actor and director (Skippy, Superman), dies at 88
- May 3 Sergo Kotrikadze, Georgian footballer (b. 1936)
- May 3 Thanasis Veggos, Greek actor (b. 1927)
- May 4 Mary Murphy, American actress (A Man Alone, Maggie-Investigators), dies at 80
- May 4 Sada Thompson, American actress (Family, Pursuit of Happiness), dies at 83
- May 5 Arthur Laurents, American playwright (West Side Story: Gypsy), and screenwriter (Rope; Anastasia), dies at 93
- May 5 Claude Choules, British-Australian sailor and last surviving combat veteran of both World War I and World War II, dies at 110
- May 5 Dana Wynter, German-English actress (Airport; Invasion of the Body Snatchers), dies at 79
- May 5 Yosef Merimovich, Israeli football player, 1948-58, and manager, 1958-89, dies at 86
- May 7 "Big" George Webley, British broadcaster, composer, bandleader and musician, dies of a heart attack at 53
- May 7 Allyson Hennessy, Trindadian television presenter
- May 7 John Walker [Maus], American rock vocalist (Walker Brothers - "The Sun Ain't Gonna Shine (Anymore)"), dies of liver cancer at 67
Seve Ballesteros (1957-2011)
May 7 Spanish golfer (British Open 1979, 84, 88, US Masters 1980, 83), dies of brain cancer at 54
- May 8 Cornell Dupree, American jazz and R&B session guitarist (Atlantic Records - Aretha Franklin), dies of emphysema at 68
- May 8 Lionel Rose, Australian boxer (WBA, WBC, The Ring bantamweight title 1968-69; first Indigenous Australian to win a world title), dies at 62
- May 9 Wouter Weylandt, Belgian cyclist, dies at 26
- May 11 (Eugene) "Snooky" Young, American jazz trumpeter who mastered the plunger mute, dies at 92
- May 12 Harry Danielsen, Norwegian educator and politician, dies at 74
- May 13 Bernard Greenhouse, American cellist (Beaux Arts Trio), dies at 95
- May 13 Bruce Ricker, American jazz and blues documentarian (The Last of the Blue Devils; Thelonious Monk: Straight, No Chaser), dies at 68
- May 13 Derek Boogaard, Canadian ice hockey player (b. 1982)
- May 13 Jack Richardson, Canadian record producer (The Guess Who), dies at 81
- May 13 Patricia Tindale, British architect and civil servant (school buildings, public housing), dies at 85
- May 15 Bob Flannigan, American jazz singer (The Four Freshmen), dies at 84
- May 16 Bill Skiles, American comic (b. 1931)
- May 16 Bob Davis, Australian football forward (All Australian captain 1958; VFL Premiership 1951, 52 Geelong FC), coach (VFL Premiership 1963 Geelong FC) and broadcaster (7 Network), dies at 82
- May 16 Edward Hardwicke, British actor (Sherlock Holmes), dies at 78
Harmon Killebrew (1936-2011)
May 17 American Baseball HOF utility (13 × MLB All-Star; AL MVP 1969; 6 × AL HR leader; Washington Senators, Minnesota Twins), dies from esophageal cancer at 74
- May 18 Leonard Kastle, opera composer, librettist, director (The Passion of Mother Ann), and film maker (The Honeymoon Killers), dies at 82
- May 19 Garret FitzGerald, Irish politician and 8th Taoiseach of Ireland (Fine Gael: 1981-87), dies at 85
- May 19 Kathy Kirby, English singer (Secret Love), dies at 72
- May 19 Phyllis Avery, American actress (Ruby Gentry, George Gobel Show, Mr Novak), dies at 88
Randy Savage (1952-2011)
May 20 American pro wrestler (WWF/SMW/ICW; WWE Hall of Fame), dies of a heart attack at 58
- May 22 Ze'ev Wolfgang Steinberg, Israeli violist and composer, dies at 92
- May 24 Huguette Clark, Heiress of the Clark Copper fortune, life-long reclusion from society. (b. 1906)
- May 25 Leonora Carrington, British-Mexican Surrealist artist, dies aged 94
- May 25 Paul Splittorff, American MLB pitcher and broadcaster (KC Royals), dies of oral cancer at 64
- May 25 Terry Jenner, Australian cricket spin bowler (9 Tests, 24 wickets; WA CA, SA CA), dies from a heart attack at 66
- May 26 Arisen Ahubudu, Sri Lankan scholar, author and playwright (b. 1920)
- May 26 Ben Roberts, British industrial relations expert (London School of Economics), dies at 93
- May 27 Gill Scott-Heron, American writer, poet and singer ("Whitey on the Moon"), dies at 62
- May 27 Jeff Conaway, American actor and singer (Taxi - "Bobby"; Grease - "Kenickie"; Babylon 5 - "Zack"), dies of pneumonia and sepsis at 60
- May 27 Margo Dydek, Polish basketball player (b. 1974)
- May 28 Alys Robi [Alice Robitaille], French Canadian cabaret and radio of French translations of Latin songs, dies at 88
- May 28 Barbara Mills, British barrister (first female Director of Public Prosecutions), dies at 70
- May 29 Bill Clements, American politician, Governor of Texas (1987-91), dies at 94
- May 29 Bill Roycroft, Australian equestrian (Olympic gold team event 1960, bronze 1968, 76), dies at 96
- May 29 Ferenc Mádl, Hungarian politician, President of Hungary (b. 1931)
- May 29 Sergei Bagapsh, Abkhazian president (b. 1949)
- May 29 Simon Brint, British comic actor, musician, and television composer (French and Saunders; A Bit of Fry & Laurie; Monarch of the Glen), takes his own life at 60
- May 30 Clarice Taylor, American actress (Nurse Bailey-Nurse), dies at 93
- May 30 Giorgio Tozzi, American operatic bass (dubbed vocals of Emile de Becque for "South Pacific" film), dies at 88
- May 30 Rosalyn Yalow, American medical physicist (Nobel 1977), dies at 89
- May 31 Andy Robustelli, American NFL defensive end (LA Rams, NY Giants), dies at 85
- May 31 Pauline Betz Addie, American tennis player (5 Grand Slam singles titles), dies of complications from Parkinson's disease at 91