- Mar 2 Interstate commerce comes under federal control
- Mar 4 The "National Institution for the Preservation of Life from Shipwreck" founded in the United Kingdom, later to be renamed The Royal National Lifeboat Institution in 1858.
- Mar 5 First Burmese War: The British officially declare war on Burma
- Mar 7 Giacomo Meyerbeers opera "Il Crociati in Egitto" (The Crusader in Egypt) premieres at La Fenice in Venice with famous castrato Giovanni Battista Velluti singing
- Mar 11 US War Department creates the Bureau of Indian Affairs
- Mar 17 Britain & Netherlands sign a trade agreement
- Mar 21 Fire at a Cairo ammunition dump kills 4,000 horses
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