- Apr 5 The first international rugby league match is played between England and an Other Nationalities team (Welsh & Scottish players) in Central Park, Wigan, England.
- Apr 8 British mystic Aleister Crowley transcribes the first chapter of the Book of the Law
- Apr 8 Entente Cordiale between Britain and France
- Apr 8 Great Britain and France establish their Entente Cordiale, a technical treaty settling long-standing disagreements over Morocco, Egypt, Africa, and the Pacific
- Apr 8 New York City changes the name of Longacre Square to Times Square, in honor of The New York Times’s move to the area
- Apr 13 A squadron of the Russian fleet is decoyed out of Port Arthur by Japanese maneuvers, when they realize they are sailing into a trap; their battleship Petropavlovsk hits a mine and sinks, with a loss of 700 men
- Apr 13 Battle of Oviumbo (in modern Namibia): Herero tribesmen rise up against German colonists
Lewis and Clark Expo Gold Dollar
Apr 13 US Congress authorizes Lewis and Clark Exposition $1 gold coin
Chesbro's 1st Win
Apr 14 NY Highlanders' future Baseball HOF pitcher Jack Chesbro's first of 41 wins this season; pitches complete game and beats Boston Americans, 8-2 at Hilltop Park, NYC
- Apr 23 American Academy of Arts & Letters forms
French President Snubs Pope
Apr 24 President Loubet of France visits King Victor Emmanuel III of Italy and pointedly ignores the Pope, exacerbating relations between France and the Roman Catholic Church
- Apr 26 Bell Telephone Company of Antwerp Belgium forms
A Humorous Diplomatic Atlas of Europe and Asia
Apr 26 General Kuroko leads the Japanese Army against the large Russian force at the Yalu river during the Russo-Japanese War
First Labour Government
Apr 27 The Australian Labor Party under Prime Minister Chris Watson becomes the first Labor government in the world
- Apr 30 Ice cream cone makes its debut at St. Louis World's Fair invented by Ernest A. Hamwi (independently of other claimant Italo Marchiony in NY)