- Mar 28 Ranuccio I Farnese, Duke of Parma and Piacenza (1592-1622), born in Parma, Italy (d. 1622)
- Apr 3 Giovanni Battista Massarengo, Italian composer, born in Parma, Duchy of Parma (d. c.1596)
- Apr 10 Emilia van Nassau, daughter of William I of Orange and Anna of Saxony, born in Cologne, Germany (d. 1629)
- Aug 31 Jahangir, 4th Mughal Emperor of India (1605-27), born in Fatehpur Sikri, Mughal Empire (d. 1627)
- Oct 18 Giambattista Marini, Italian poet (d. 1625)
- Nov 11 Martin Ruland the Younger, German physician and alchemist, born in Lauingen, Bavaria, Germany (d. 1611)
- Nov 16 Paul Sartorius, German composer, born in the Free Imperial City of Nuremberg, Holy Roman Empire (now Germany) (d. 1609)
- Nov 27 Ottavio Vernizzi, Italian composer, born in Bologna, Papal States (now Italy) (d. 1649)
- Dec 18 Jakob Hassler, German composer, born in the Free Imperial City of Nuremberg, Holy Roman Empire (d. 1622)
- Dec 30 Georg Quitschreiber, German composer, born in Kranichfeld, Electorate of Saxony (d. 1638)