- Mar 16 René Le Bossu, French critic (d. 1680)
- Apr 6 Vincenzo De Grandis, Italian composer and priest, born in Ostra, Papal States (d. 1708)
- Apr 8 Cornelis de Heem, Dutch painter, born in Leiden, Netherlands (d. 1695)
- Jul 15 Jens Juel, Danish diplomat and statesman at the Danish-Norwegian court, born at Nørtorp, Jutland (d. 1700)
John Dryden (1631-1700)
Aug 9 English poet ("Absalom and Achitophel"), satirist ("Mac Flecknoe"; "The Medall") and playwright who was the first English Poet Laureate (1668-1700), born in Aldwincle, Northamptonshire, England [1]
- Sep 7 Clemens Thieme, German composer, born in Grossdittmannsdorf (d. 1668)
- Sep 30 William Stoughton, American judge at the Salem witch trials (d. 1701)
- Oct 3 Sebastian Anton Scherer, German composer, born in Ulm, Baden-Württemberg, Germany (d. 1712)
- Nov 4 Mary, 1st British Princess Royal and the Princess of Orange, born in St James's Palace, London (d. 1660)
- Dec 14 Anne Conway, English philosopher, born in London (d. 1679)
- Dec 28 Ludolf Backhuysen, Dutch seascape painter and cartoonist, born in Emden (d. 1708)