- Jan 20 Pascal Boyer, French composer, born in Tarascon, Provence, France (d. 1794)
- Jan 21 John Fitch, American inventor (had a working steamboat years before Fulton), born in Windsor, Connecticut (d. 1798)
- Feb 8 Louis d'Affry, French general, military governor of Switzerland and mayor of Freiburg, born in Freiburg im Üechtland, Switzerland (d. 1810)
Joseph Banks (1743-1820)
Feb 13 English botanist and naturalist who accompanied James Cook on board the Endeavour, born in London
Thomas Jefferson (1743-1826)
Apr 13 3rd President of the United States (1801-09), born in Albemarle County, Virginia
- Apr 24 Edmund Cartwright, English inventor (power loom), born in Marnham, Nottinghamshire, England (d. 1823)
- Apr 30 Robert Jasper van der Capellen, Dutch politician and Master of Marsch, born in Eefde, Zutphen, Netherlands (d. 1814)
- May 17 Seth Warner, American revolutionary leader, born in Roxbury, Connecticut (d. 1784)
Toussaint Louverture (1743-1803)
May 20 Haitian general, revolutionary and most famous of the leaders of the Haitian Revolution, born in Cap-Français, French colony of Saint-Domingue
Jean-Paul Marat (1743-1793)
May 24 French journalist and revolutionary (Friend of the People periodical), born in Boudry, Prussia
- Jun 8 Alessandro Cagliostro [Giuseppe Balsamo], Italian adventurer and magician (Prince of Quacks), born in Palermo, Sicily (d. 1795)
- Jun 20 Anna Laetitia Barbauld, English poet and writer of hymns (Life! I Know Not What Thou Art), born in Kibworth Harcourt, Leicestershire, England (d. 1825)
- Jun 30 Niels Schiørring, Danish musician and composer, born in Favrskov Municipality, Denmark (d. 1798)
- Jul 3 Sophia Magdalena of Denmark, Queen consort of Sweden, born in Christiansborg Palace, Copenhagen, Denmark (d. 1813)
- Jul 14 Gavrila Romanovich Derzhavin, Russian poet and statesman, born in the Kazan Governorate, Russian Empire (d. 1816)
- Jul 31 August van Hekeren van Suideras, Dutch mayor and orangist (d. 1811)
- Aug 19 Marie Jeanne Becu, Comtesse du Barry, last mistress of Louis XV, born in Vaucouleurs, France (d. 1793)
- Aug 26 Antoine-Laurent Lavoisier, father of modern chemistry (identified oxygen and hydrogen), born in Paris, France (d. 1794)
Marquis de Condorcet (1743-1794)
Sep 17 Marquis de Condorcet, French enlightenment philosopher (Condorcet Method) and mathematician, born in Ribemont, Picardy, France
- Sep 22 Quintin Craufurd, British author (friend of Marie Antoinette), born in Kilwinning, Scotland (d. 1819)
- Sep 30 Jeronymo Francisco de Lima, Portuguese composer (Dixit Dominus), born in Lisbon, Portugal (d. 1822)
- Oct 5 Giuseppe Gazzaniga, Italian composer, born in Verona, Republic of Venice (d. 1818)
- Nov 11 Carl Peter Thunberg, Swedish naturalist, born in Jönköping, Sweden (d. 1828)
- Dec 1 Martin Heinrich Klaproth, German chemist (discovered uranium), born in Wernigerode, Brandenburg (d. 1817)
- Dec 6 Franz Nikolaus Novotny, Austrian composer, born in Eisenstadt, Austria (d. 1773)
- Dec 23 Ippolit Bogdanovich, Russian author and poet (Dushenka), born in Perevolochna, Cossack Hetmanate (d. 1803)