What Happened in 1465
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- Feb 4 Frans van Brederode, Dutch rebel (Hook faction), born in Vianen (d. 1490)
- Dec 11 Ashikaga Yoshihisa, Japanese 9th shōgun of the Ashikaga shogunate, born in Kyoto, Japan (d. 1489)
- Jan 5 Charles, Duke of Orléans, French poet, dies at 70
- Mar 30 Isabella of Clermont, Queen of Naples as wife of Ferdinand I and heir to principality of Taranto, dies at abut 40
- May 12 Thomas Palaeologus, Despot of the Despotate of Morea dies in Rome at about 56