- Apr 10 Michael Tarchaniota Marullus, Greeks poet, drowns in full armor, along with his horse in Volterra, Republic of Florence, while travelling to join a battle, at age 41 or 42
Bartolomeu Dias (c. 1450-1500)
May 29 Portuguese explorer (1st European to round Cape of Good Hope), drowns at 48 or 49
- Sep 12 Albert III, Duke and ruler of Saxony, dies at 57
- Sep 15 John Morton, English Archbishop of Canterbury (1486-1500) (b. c. 1420)
- Oct 1 John Alcock, English bishop and chancellor (founded Jesus College, Cambridge), dies at about 70
- Oct 21 Go-Tsuchimikado, 103rd Emperor of Japan (1464-1500), dies at 58
Assassination
Drug Overdose
Gunshot Wound
Murder
Plane Crash
Suicide