- Feb 23 Herman Herbertsz, vicar, dies at about 60
- Mar 11 Giovanni Maria Nanino, Italian composer
- Apr 15 Cornelius Kilianus, Flemish translator & poet, dies at ~78
- Apr 25 Don Juan Alvarez, Spanish Admiral (Gibraltar), dies in battle
- Apr 25 Jacob van Heemskerck, Dutch Admiral (Nova Zambia), dies in battle
- May 21 John Rainolds, English scholar (b. 1549)
- Jun 10 John Popham, English politician (Speaker of the House, Lord Chief Justice), dies at 75 or 76
- Jun 30 Caesar Baronius, Italian cardinal and historian, dies at 68
- Jul 20 Paulus Merula, Dutch lawyer and historian (Historia Belgica), dies at 48
- Aug 22 Bartholomew Gosnold, English explorer and privateer (b. 1572)
- Sep 5 Pomponne de Bellièvre, French statesman (Chancellor of France0, dies (b. 1529)
- Sep 10 Luzzasco Luzzaschi, Italian composer and organist, at about 63 [birth date unconfirmed]
- Sep 22 Alessandro Allori, Italian Mannerist painter and director of the Florentine carpet factory, dies at 72
- Oct 26 Philipp Nicolai, German Lutheran pastor, poet, composer and hymnodist, dies at 52
Assassination
Car Crash
Hanging
Killed in Action
Plane Crash
Poisoning