- Apr 7 El Greco, Greek-born artist working in Spain (b. 1541)
- May 3 Sasbout Vosmeer, Dutch Catholic theologist and apostole vicar, dies at 66
- Jun 15 Henry Howard, 1st Earl of Northampton, English politician (b. 1540)
- Jul 1 Isaac Casaubon, English classical scholar (Atheneaus), dies at 55
- Jul 14 Camillus de Lellis, Italian Roman Catholic saint (founder of the Ministers of the Sick), dies at 64
- Jul 15 Pierre de Bourdeille, seigneur de Brantôme, French historian and biographer (b. c.1540)
- Aug 11 Lavinia Fontana, Italian painter, dies at 61
Elizabeth Báthory (1560-1614)
Aug 21 Hungarian countess and the world's most prolific female serial killer, dies at 54
Assassination
Drug Overdose
Gunshot Wound
Murder
Plane Crash
Suicide