- Jan 6 Fanny Burney, English novelist (Camille, Evalina), dies at 87
- Jan 10 Princess Elizabeth of the United Kingdom, 7th child and 3rd daughter of King George III and Charlotte of Mecklenburg-Strelitz, dies at 69
- Jan 22 Johann Friedrich Blumenbach, German anthropologist (b. 1752)
- Jan 30 Juan Galindo, Irish-Honduran soldier, diplomat for Federal Republic of Central America and early Maya archaeologist, killed in battle at about 38
- Feb 18 Jeffry Wyatville, English architect and garden designer (alterations and extensions to Chatsworth House and Windsor Castle), dies at 73
- Mar 2 Wilhelm Olbers, German astronomer and physician who discovered asteroids (Pallas & Vesta), dies at 81
- Mar 12 Friedrich Westenholz, German composer, dies at 61
- Mar 22 Étienne Bobillier, French mathematician, dies at 41
- Mar 23 William Maclure, Scottish-American geologist (first geological map), dies at 76
- Mar 28 Simon-Antoine-Jean Lhuillier, Swiss mathematician, dies at 89
Beau Brummell (1778-1840)
Mar 30 English dandy famous for his fashion style of simplicity and elegance, dies of syphilis at 61
- Apr 17 Hannah Webster Foster, American author (The Coquette; or, The History of Eliza Wharton), dies at 81
- Apr 19 Jean-Jacques Lartigue, Roman catholic bishop of Montreal (b. 1777)
- Apr 25 Siméon-Denis Poisson, French mathematician (Poisson distribution) and physicist, dies at 58
- May 5 Gottlob Benedikt Bierey, German composer, dies at 67
- May 5 Matthäus Fischer, German organist and composer, dies at 76
- May 6 Francisco de Paula Santander, Colombian president and independence leader (b. 1792)
- May 7 Caspar David Friedrich, German painter, chiefly of landscapes with contemplative figures in the Romantic style, dies at 65
- May 26 Sidney Smith, British admiral, dies at 75
- May 27 Niccolo Paganini, Italian composer and violin virtuoso (Princess Lucca), dies at 57
- May 30 Dominique Jacques de Eerens, Dutch general and politician (Governor-General of Dutch East Indies 1836-40), dies in office at 59
- Jun 6 Marcellin Champagnat, French priest (b. 1789)
- Jun 7 Frederik Willem III, King of Prussia (1797-1840), dies at 69
- Jun 19 John Cockerill, English-Belgian industrialist (founded iron, steel, and manufacturing company - John Cockerill & Company), dies at 50
- Jun 25 Leopold Karel, Count of Limburg Stirum, Dutch general and politician who was part of the 1812 Triumvirate in the Netherlands, dies at 82
- Jun 29 Lucien Bonaparte, Corsican-French prince of Canino and Musignano (younger brother of Napoleon Bonaparte), dies of cancer at 65
Karl Ferdinand von Graefe (1787-1840)
Jul 4 German surgeon who helped create modern plastic surgery, dies at 53
- Jul 21 Moses Waddel, American educator, minister and bestselling author (Memoirs of the Life of Miss Caroline Elizabeth Smelt), dies at 70
- Jul 22 Józef Javurek, Polish-Russian composer, dies at 83
- Jul 23 František Max Kníže, Czech composer, dies at 55
- Aug 4 José María Narváez, Spanish naval officer and explorer (led 1st European expedition to explore Strait of Georgia), dies (b. 1768)
- Aug 18 Antony Christiaan Winand Staring, Dutch lawyer and poet (Jaromir), dies at 73
- Aug 24 Joseph Waast Aubert Nonot, French organist (St Géry in Cambrai, 1768-83), and composer, dies at 89
- Aug 25 Karl Leberecht Immermann, German writer, dies at 44
- Aug 27 William Kneass, 3rd US chief engraver (1824-40), dies in office
- Sep 8 John Hendricus van de Palm, Dutch linguist and theologist, dies at 77
- Sep 11 Johannes Hendricus van der Palm, Dutch theologist and Minister of Education, dies at 77
- Sep 15 Franz Pecháček, Austrian-German composer, dies at 47
- Sep 22 Anne Lister, English diarist 'the 1st modern lesbian', dies of a fever at 49
- Sep 22 Princess Augusta Sophia of the United Kingdom, 6th child and second daughter of King George III and Queen Charlotte, dies at 71
- Sep 25 Jacques Macdonald, Duc de Tarente, Scottish-French general under Napoleon, dies at 74
- Oct 6 François Budan de Boislaurent, French mathematician, dies at 80
- Oct 18 Pierre-Gabriel Gardel, French ballet dancer and choreographer (In L'Offrande à la Liberté), dies at 82
- Nov 24 Cornelis Rudolph Theodorus Krayenhoff, Dutch hydraulic engineer (began Defense Line of Amsterdam), cartographer and soldier, dies at 82
- Nov 27 William Giblin, Australian lawyer and politician (Premier of Tasmania, 1878 & 1879-84), born in Hobart, Van Diemen's Land (now Tasmania) (d. 1887)
- Dec 11 Emperor Kōkaku of Japan (1780-1817), dies at 69