- Sep 1 Jon Polito, American actor (Fire With Fire, Homicide: Life on the Street), dies from multiple myeloma at 65
- Sep 1 Len Maddocks, Australian cricket wicket-keeper (7 Tests, 19 dismissals; Victoria, Tasmania), dies at 90
- Sep 1 Raymond Daveluy, Canadian organist (St. Joseph's Montreal, 1960-2002), composer and educator, dies at 89
- Sep 2 Islam Karimov, President of Uzbekistan (1991-2016), dies at 78
- Sep 4 David Jenkins, English controversial cleric (Bishop of Durham), dies at 91
- Sep 4 Ralph Goings, American photorealistic painter, dies at 88
- Sep 5 Duane Graveline, American doctor and astronaut, dies at 85
- Sep 5 Hugh O'Brian, American actor (Wyatt Earp, Search), dies at 91
Phyllis Schlafly (1924-2016)
Sep 5 American right-wing crusader, Eagle Forum President, dies at 92
- Sep 6 Lewis Merenstein, American record producer (Miriam Makeba; Van Morrison's Astral Weeks; Glass Harp), dies of pneumonia at 81
- Sep 6 Raymond Hide, British geophysicist (geomagnetism, meteorology, geodesy and oceanography), dies at 87
- Sep 7 Cary Blanchard, American NFL kicker (Indianapolis Colts), dies of a heart attack at 47
- Sep 7 Ken Higgs, English cricket fast bowler (15 Tests, 71 wickets, 1 x 50; Lancashire CCC, Leicestershire CCC), dies at 79
- Sep 7 Norbert Schemansky, American weightlifter (Olympic gold heavyweight 1952, silver 1948, bronze 1960, 64), dies at 92
- Sep 8 Johan Botha, South African operatic tenor, dies of liver cancer at 51
- Sep 8 Prince Buster [Cecil Bustamente Campbell], Jamaican singer-songwriter and producer ("Al Capone"; "Madness", "Whine and Grine"), dies at 78 [1]
- Sep 8 The Lady Chablis [Benjamin Knox], American transgender entertainer (Midnight in the Garden of Good and Evil), dies at 59
- Sep 9 James Stacy [Maurice William Elias], American actor (Lancer), dies at 79
- Sep 10 Eddie Antar, founder and CEO (Crazy Eddie Electronics Store), dies at 68
- Sep 10 Knut Wiggen, Norwegian computer music pioneer and composer, dies at 89
- Sep 11 Alexis Arquette, American transgender performer (Last Exit to Brooklyn), dies at 47
- Sep 12 Ali Javan, Iranian American physicist and inventor (Helium-Neon Laser), dies at 89 [1]
- Sep 12 Hidayat Inayat Khan, British-French classical composer, conductor and Sufi teacher, dies at 99
- Sep 15 Rose Mofford, American politician, 1st female Governor of Arizona (1988-1991), dies at 94
- Sep 16 Carlo Azeglio Ciampi, Italian President (1999-2006) and Prime Minister (1993-94), dies at 95
Edward Albee (1928-2016)
Sep 16 American playwright (Who's Afraid of Virgina Woolf?), dies at 88 [1]
- Sep 17 Charmian Carr, American actress (The Sound of Music), dies at 73
- Sep 20 Bill Barrett, American politician (Rep-R-Nebraska 1991-2001), dies at 87
- Sep 20 Curtis Hanson, American film director and screenwriter (LA Confidential, 8 Mile), dies at 71
- Sep 21 John D. Loudermilk, American country singer and songwriter ("Tobacco Road"; "Then You Can Tell Me Goodbye"), dies of cancer at 82
- Sep 22 Kjell Albin Abrahamson, Swedish journalist and writer, dies at 71
- Sep 24 Bill Nunn, American actor (Do the Right Thing), dies at 63
- Sep 24 Buckwheat Zydeco [Stanley Dural, Jr.], American B-3 organist, accordionist and singer ("Where There's Smoke, There's Fire"), dies of lung cancer at 68
Arnold Palmer (1929-2016)
Sep 25 American golfer (7 major titles; US Masters 1958, 60, 62, 64), dies of heart failure at 87
- Sep 25 Jean Shepard, American country singer (Ozark Jubilee), dies of Parkinson's disease at 82
- Sep 25 José Fernández, Cuban-American MLB player (Miami Marlins), dies in a boat accident at 24
- Sep 25 Kashif Saleem [Michael Jones], American R&B, disco, and soul keyboardist (B.T. Express, 1976-79 - "Can't Stop Groovin' Now, Wanna Do It Some More"), songwriter, and record producer, dies at 59
- Sep 25 Rod Temperton, British pop musician and songwriter ("Boogie Nights"; "Thriller"; "Give Me the Night"; "Yah Mo B There"), dies of cancer at 66
- Sep 27 Randy Duncan Jr., American College Football HOF quarterback (University of Iowa; #1 pick 1959 NFL Draft by GB Packers), dies from brain cancer at 79
- Sep 28 Agnes Nixon, American television producer, director and writer (One Life to Live; All My Children), dies at 93
- Sep 28 Gloria Naylor, American author (Women of Brewster Place), dies at 66
- Sep 28 Max Walker, Australian cricket fast bowler (34 Tests, 138 wickets) and broadcaster (Nine Network), dies at 68
Shimon Peres (1923-2016)
Sep 28 Polish-Israeli Labor Party politician (President. 2007-14; Prime Minister, 1984-86 and 1995-96; Foreign Minister, 1986-88, 1992-95, and 2001-02), and Nobel Peace Prize Laureate (1994), dies of a stroke at 93
- Sep 30 Oscar Brand, Canadian-born American folk vocalist (Draw Me a Laugh), dies at 96
Assassination
Car Crash
Hanging
Killed in Action
Plane Crash
Poisoning