William Pitt the Younger (1759-1806)
Jan 23 British Prime Minister (Tory: 1783-1801, 1804-06), dies of a suspected peptic ulceration of his stomach or duodenum at 46
- Feb 11 Vicente Martín y Soler, Valencian composer, dies at 51
- Feb 19 Elizabeth Carter, English poet, bluestocking and translator (All the Works of Epictetus Which Are Now Extant), dies at 88
- Feb 20 Lachlan McIntosh, Scottish-born American military and political leader (b. 1725)
- Feb 23 John Alcock, English composer and organist, dies at 90
- Feb 24 John Nieuwenhuijzen, Dutch theologist (co-founder Foundation 't Nut), dies at 81
- Mar 3 Heinrich Christian Boie, German author and editor, dies at 61
- Mar 16 Giuseppe Colla, Italian composer, dies at 74
- Mar 17 David Dale, Scottish industrialist & philanthropist (cotton magnate who implemented advanced social and educational conditions), dies at 67
- Mar 23 George Pinto [Sanders], English violin prodigy, keyboard virtuoso, and composer, dies of tuberculosis at 20
- Apr 4 Friedrich Gottlob Fleischer, composer, dies at 84
- Apr 9 William V of Orange, Stadtholder of the Dutch Republic, dies at 58
Horatio Gates (1727-1806)
Apr 10 British-American soldier (general of the Continental Army during the Revolutionary War), dies at 78
Robert Morris (1734-1806)
May 8 English-born merchant and American founding father who signed the US Declaration of Independence, dies at 72
- May 21 Maria Antonia of Naples and Sicily, Princess of Asturias, dies at 21
- May 24 John Campbell, 5th Duke of Argyll, British field marshal (b. 1723)
- Jun 8 George Wythe, US attorney (signed US Declaration of Independence), dies at about 79
- Jun 23 Mathurin Jacques Brisson, French zoologist and naturalist (Ornithologie), dies at 83
- Jun 28 Johann Friedrich Ludwig Sievers, German composer, dies at 64
- Jul 10 George Stubbs, British animal painter (Horse Frightened by Lion), dies at 81
- Jul 11 James Smith, Irish/US attorney/signer (Declaration of Independence), dies at 87
- Aug 9 Louis Ferdinand, Prussian prince and a soldier in the Napoleonic Wars, dies at 33
- Aug 10 Michael Haydn, Austrian composer, dies at 68
- Aug 22 Jean-Honoré Fragonard, French painter (The Swing), dies at 74
- Aug 23 Charles Augustin de Coulomb, Fren physicist (coulometrie), dies at 70
- Sep 8 Patrick Cotter O'Brien, Irish showman, first known eight-foot-tall person (stood 8-feet, 1-inch (246cm), dies from strain of gigantism at 46 [1]
- Sep 9 William Paterson, American jurist and statesman (b. 1745)
- Sep 10 Johann Christoph Adelung, German linguist, librarian, translator and lexicographer, dies at 74
- Sep 12 Christian Gottfried Thomas, German composer, publisher, and musicologist, dies at 58
- Sep 13 Charles James Fox, English politician (b. 1749)
Benjamin Banneker (1731-1806)
Oct 9 African American astronomer, mathematician and surveyor of Washington, D.C., dies at 74
Henry Knox (1750-1806)
Oct 25 American general (Continental Army and later the United States Army) and 1st US Secretary of War (1785-94), dies at 56 after swallowing a chicken bone which lodged in his throat and caused a fatal infection
- Oct 26 John Graves Simcoe, British Army general and 1st Lieutenant Governor of Upper Canada (1791-96), dies at 54
- Oct 28 Charlotte Turner Smith, British poet and novelist (b. 1749)
- Oct 31 Sophie Mereau, German writer, dies at 36
- Oct 31 Utamaro Kitagawa, Japanese painter and printmaker of the ukiyo-e movement, dies at about 53
- Nov 10 Charles William Ferdinand, German military leader (Prussian army general) and nobleman (Duke of Brunswick, 1780-1805), dies at 71
- Nov 12 Josef Gottlieb Kölreuter, German Botanist who pioneered the study of plant hybrids, dies at 73
- Nov 16 Moses Cleaveland, founder of Cleveland, Ohio (b. 1754)
- Nov 19 Shah Alam II, 17th Mughal Emperor (1760-1806), dies at 78
- Nov 23 Roger Newdigate, British politician (sat in the House of Commons 1742-80), dies at 87
- Dec 14 John Breckinridge, American lawyer (5th United States Attorney General) and politician (U.S. Senator from Kentucky), dies at 46
- Dec 22 William Vernon, American merchant (b. 1719)