- Feb 11 Battle at Wayna Daga: Ethiopian and Portuguese troops beat Muslim army
Anti-French Covenant
Feb 11 Holy Roman Emperor Charles V and English King Henry VIII sign anti-French covenant
De Humani Corporis Fabrica
Jun 1 Flemish physician Andreas Vesalius publishes "De humani corporis fabrica (On the fabric of the human body in seven books)" a major step forward in understanding human anatomy [date is representative as exact date of publication unknown]
Queen of Scots Crowned
Sep 9 Mary Stuart, at nine months old, is crowned "Queen of Scots" in the central Scottish town of Stirling
Gregory I
Gregory XIII
Julius II
Julius III
Leo X
Pius V