Lewis and Clark Expedition
Apr 7 Lewis and Clark Expedition leaves Fort Mandan (on the Missouri River near what is now Washburn, North Dakota), beginning their journey to the Pacific Ocean
Eroica
Apr 7 Premiere of Ludwig van Beethoven's "Eroica" (Symphony No. 3), at the Theater an der Wien, Vienna, conducted by the composer; contemporary reviews were mixed
- Apr 27 US Marines attack shores of Tripoli