Die Eerste Walpurgisnacht
Jan 10 Felix Mendelssohn's cantata "Die erste Walpurgisnacht" premieres in Berlin, Germany
- Jan 15 HMS Beagle anchors at Goeree Tierra del Fuego
- Jan 23 Joseph Pease becomes the first Quaker to be admitted to the UK Parliament on his affirmation
- Mar 17 Phoenix Society forms (NY)
- Mar 20 US & Siam sign commercial treaty
- Apr 4 St Etienne-Lyons railway fully opens in France
- Apr 9 1st US tax-supported public library in Peterborough, New Hampshire
- Apr 24 Jacob Evert & George Dulty patent 1st soda fountain
- May 2 Russian Tsar Nicolas I bans the public sale of serfs
- May 11 "Lady-of-the-Lake" strikes iceberg & sinks in North Atlantic; kills 215
- Jun 3 4th national black convention meets (Philadelphia)
Ada Lovelace Meets Charles Babbage
Jun 5 Future 1st computer programmer Ada Lovelace meets mathematician and inventor Charles Babbage
- Jun 27 Prudence Crandall, a white woman, arrested for conducting an academy for black females at Canterbury, Connecticut
- Jun 28 Three missionaries of the Paris Evangelical Missionary Society obtain permission from Chief Moshoeshoe (Moshesh) to found a mission station in Basutoland (now Lesotho)
- Jul 8 Russia and Turkey sign defense treaty
- Jul 23 Cornerstones are laid for the construction of the Kirtland Temple in Kirtland, Ohio
- Jul 24 HMS Beagle departs Maldonado, Uruguay
- Aug 3 HMS Beagle reaches river mouth of Rio Negro
- Aug 10 Chicago incorporates as a village of about 200
- Aug 12 The town of Chicago is incorporated (population 350)
- Aug 24 HMS Beagle reaches Bahia Blanca, Argentina
Britain Abolishes the Slave Trade
Aug 28 Britain's Slavery Abolition Act gains royal assent
Fighting The Scourge of Child Labour
Aug 29 Britain’s 1st Factory Act becomes law "to regulate the Labour of Children and young Persons in the Mills and Factories of the United Kingdom"
Darwin Arrives in Buenos Aires
Sep 20 Charles Darwin arrives in Buenos Aires after travelling through the Argentine interior with guachos
Hightstown Derailment
Nov 8 Train derails at Hightstown, New Jersey, killing two people. Also onboard are Cornelius Vanderbilt and former President John Quincy Adams.
"Lucrezia Borgia"
Dec 26 Gaetano Dinozetti's opera "Lucrezia Borgia" premieres at La Scala Teatro in Milan, Italy