Henry Appointed Heir Apparent
Feb 18 Henry Tudor (later Henry VIII) appointed Prince of Wales, heir apparent to the English throne
Michelangelo's 12 Apostles
Apr 24 Michelangelo undertakes to carve 12 Apostles for the Cathedral of Florence, each four and a quarter braccia high (248.2cm), at the rate of at least one completed statue per year. He produced only one, of St. Matthew, and that remained unfinished.
- Apr 28 Battle at Cerignalo: Spanish army under Gonzalo Fernández de Córdoba defeats a French force led by Louis d'Armagnac, Duke of Nemours
Columbus Discovers Caymans
May 10 Christopher Columbus is the first European to discover the Cayman Islands, names them Las Tortugas after its sea turtles
Michelangelo Sculpts the 12 Apostles
Sep 11 Michelangelo begins sculpting the 12 Apostles for the Cathedral of Florence, over-life-sized marble statues of which only 1 was partly finished, that of St. Matthew
- Oct 30 Queen Isabella of Spain bans violence against Indians in the Americas
- Dec 29 Battle of Garigliano: Spanish army under Gonzalo Fernández de Córdoba defeats French forces in Italy, giving Spain control of the Kingdom of Naples
Gregory I
Gregory XIII
Julius II
Julius III
Leo X
Pius V