German Beer Purity Law
Apr 23 Duke Wilhelm IV of Bavaria endorses "The German Beer Purity Law" (Reinheitsgebot) and adds to it standards for the sale of beer in Bavaria, ensuring beer is only brewed from three ingredients – water, barley, and hops
- Aug 13 The Treaty of Noyon between France and Spain is signed. Francis recognises Charles's claim to Naples, and Charles recognises Francis's claim to Milan.
- Aug 24 Battle of Marj Dabiq: Ottoman forces decisively beat the Mamluk Sultanate
- Oct 28 Battle of Yaunis Khan: Turkish forces under the Grand Vizier Sinan Pasha defeat the Mameluks near Gaza
- Nov 29 Treaty of Freiburg: French/Swiss "eternal" peace treaty
Gregory I
Gregory XIII
Julius II
Julius III
Leo X
Pius V