Charles V Abdicates
Jan 16 Holy Roman Emperor Charles V abdicates his role as King of Spain and appoints his son Philip II of Spain
- Jan 23 Shaanxi Earthquake, the deadliest ever recorded, kills 830,000 in Shaanxi Province, China
Knight of the Golden Fleece
Jan 27 William I of Orange becomes a Knight of the Order of the Golden Fleece
- Feb 14 English Archbishop Thomas Cranmer declared a heretic
- Mar 22 Cardinal Reginald Pole becomes archbishop of Canterbury
- Mar 28 Origin of Fasli Era (India)
- Mar 28 Philip II of Spain is formally crowned King of Spain
- Apr 13 Portuguese converted Christian Marranos who revert to Judaism burned by order of Pope
- Aug 27 Holy Roman Emperor Charles V abdicates in favor of his brother Ferdinand I