- Feb 4 Reformer and bible translator John Roger is the first protestant martyr under Mary I, when he is burnt at the stake at Smithfield, London
- Feb 9 Bishop of Gloucester John Hooper is burned at the stake for heresy
- Apr 9 Marcello Cervini elected Pope Marcellus II
- Apr 17 Siena surrenders to Spanish troops
William I of Orange
Nov 17 William I of Orange becomes member of Council of State