- Jan 28 By Edict of Orleans French persecution of Huguenots is suspended
- Jul 2 Menas, Emperor of Ethiopia, defeats a revolt in Emfraz
- Jul 12 "Trinity Church" (now Saint Basil's Cathedral) is consecrated in Moscow, Russia, built to commemorate defeat of the Mongols at battle of Kazan
- Jul 12 Diego de Lando, Bishop of Yucatan, burns on a large pyre Maya religious objects and most of the last surviving books of bark outside the Franciscan convent of Maní
Queen of Scots Assumes Throne
Aug 19 Mary Queen of Scots arrives in Leith, Scotland to assume the throne after spending 13 years in France
Conference of Poissy
Sep 9 Conference of Poissy: Religious theologians gathered by Catherine de' Medici
Spanish Florida
Sep 23 King Philip II of Spain forbids Spanish settlements in Florida